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Drug Discovery / Compound Management Services
Effectively instituting combinatorial chemistry and high-throughput screening as a
means of discovering new drugs requires an efficient and responsive system for managing
chemical compounds. Many companies have found that they can put the sophisticated
screening technologies in place, only to find that compound management processes and
systems cannot keep up the pace.
Separate emphasis needs to be placed on compound management initiatives. A typical
project may include the following steps:
| Define the strategies and business environment involving HTS and combinatorial
chemistry, especially identifying the future users of the compound inventory
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| Define the needs for numbers and sources of future compounds
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| Define the user needs for compounds including amounts, solvent, concentration, plate
formats, stability, delivery times, volumes, etc.
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| Define processes for acquiring and managing neat compounds, solubilized compounds,
source plates, and screening plates
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| Define user requirements for information systems, including interfaces to
bioinformatics and screening systems
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| Implementing compound inventory management and plate management systems
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| Implementing robotics to automate compound management and plate preparation
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